- Laboratory guidelines for fluid and electrolyte therapy in neonates.

Laboratory guidelines for fluid and electrolyte therapy in neonates.

Intravenous fluids should be increased in the presence of
1. Increased weight loss (>3%/day or a cumulative loss >20%)
2. Increased serum sodium (Na>145 mEq/L)
3. Increased urine specific gravity>1.020 or urine osmolality >400 mosm/L,
4. Decreased urine output (<1 ml/kg/hr).

Similarly fluids should be restricted in the presence of
1. Decreased weight loss (<1%/day or a cumulative loss <5%),
2. Decreased serum sodium in the presence of weight gain (Na<130),
3. Decreased urine specific gravity <1.005 or urine osmolality <100 mosm/L,
4. Increased urine output (>3 ml/kg/hr)