- 47, XYY syndrome.

47, XYY syndrome

Also known as Jacobs syndrome

This affects 1 in 1000 live-born boys.

These males are phenotypically normal but tend to be tall.

But affected boys may have hypotonia, hand trembling or involuntary muscle movements, delayed or difficult speech and delayed motor skill development.

Intelligence is usually within normal limits but there is an increased incidence of behavioral abnormalities.

Treatment:

·       speech therapy for speech delay.

·       occupational therapy: for delayed motor skill development.

·       Educational therapy: for learning disabilities.